2025 IRG-2: Hierarchical Assembly of Conductive Fibers from Coiled-Coil Peptide Building Blocks

April 4, 2025

The paper describes the use of a short protein (peptide) sequence feature to control self-assembly using pH. We showed that this control allows access to structures unprecedented in nature or computationally designed protein assemblies. The resulting nanowires are electronically conductive, with promising applications in biosensors, implants, and bioenergy devices. Learn more

Grosvirt-Dramen, A.; Urbach, Z. J.; Hurst, P. J.; Kwok, C. E.; Patterson, J. P.; Wang, F.; Hochbaum, A. I. ACS Nano 2025 19 (10), 10162-10172

This work has been published in ACS Nano. The research supported important contributions on controlling nanowire assembly by UCI undergraduate Elaine Kwok and was completed in collaboration with CCAM members Adam Grosvirt-Dramen, Zachary J. Urbach (former JRF), Paul Hurst (former JRF), Joe Patterson and Allon Hochbaum.

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